CD31 antibody - 351 011

CD31 is an endothelial cell marker
Mouse monoclonal purified IgG
Cat. No.: 351 011
Amount: 100 µg
Price: $415.00
Cat. No. 351 011 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P: not recommended
FACS: yes
Clone 10F7
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 26 to 601 from human CD31 (UniProt Id: P16284)
Reactivity Reacts with: human (P16284).
Other species not tested yet.
Specificity Recognizes all CD 31 isoforms.
Data sheet 351_011.pdf

References for CD31 - 351 011

Efficient immunoaffinity chromatography of lymphocytes directly from whole blood.
Mohr F, Przibilla S, Leonhardt F, Stemberger C, Dreher S, Müller TR, Fräßle SP, Schmidt GP, Kiene ML, Stadler H, Busch DH, et al.
Scientific reports (2018) 81: 16731. 351 011 FACS; tested species: human
Cat. No.: 351 011
Amount: 100 µg
Price: $415.00
Efficient immunoaffinity chromatography of lymphocytes directly from whole blood.
Mohr F, Przibilla S, Leonhardt F, Stemberger C, Dreher S, Müller TR, Fräßle SP, Schmidt GP, Kiene ML, Stadler H, Busch DH, et al.
Scientific reports (2018) 81: 16731. 351 011 FACS; tested species: human
Background

CD31 or platelet/endothelial cell adhesion molecule-1 (PECAM-1) is a cell adhesion molecule that contains a single trans-membrane domain and 6 Ig-like C2-type (immunoglobulin-like) domains (1). It is expressed on the surface of leukocytes and platelets and is primarily concentrated at endothelial cell-cell junctions (2). CD31 plays a role in several important biological processes, such as vascular development, maintenance of vascular endothelial barrier function and leukocyte emigration at inflammatory sites. In addition, CD31 promotes cancer metastasis by inducing epithelial-mesenchymal transition (3).