HistoSure - Neuropeptide Y

Cat. No.: 394 004

Amount: 100 µl

Price: $370.00

Cat. No. 394 004	100 µl antiserum, lyophilized. For reconstitution add 100 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: not tested yet IP: not tested yet ICC: 1 : 500 up to 1 : 1000 gallery IHC: 1 : 500 up to 1 : 1000 gallery IHC-P: 1 : 500 gallery Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section. Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section. Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section. Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section. Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen	Synthetic peptide corresponding to AA 1 to 16 from mouse Neuropeptide Y (UniProt Id: P57774)
Reactivity	Reacts with: mouse (P57774), rat (P07808). Other species not tested yet.
Specificity	Specific for Neuropeptide Y. May cross-react to PYY due to sequence homology.
Data sheet	Datasheet 394_004

References for Neuropeptide Y - 394 004

CaMKIIα Promoter-Controlled Circuit Manipulations Target Both Pyramidal Cells and Inhibitory Interneurons in Cortical Networks.
Veres JM, Andrasi T, Nagy-Pal P, Hajos N
eNeuro (2023) 104: . 394 004 IHC; tested species: mouse

Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy.
Lentini C, d'Orange M, Marichal N, Trottmann MM, Vignoles R, Foucault L, Verrier C, Massera C, Raineteau O, Conzelmann KK, Rival-Gervier S, et al.
Cell stem cell (2021) : . 394 004 IHC; tested species: mouse

Activity-dependent reconnection of adult-born dentate granule cells in a mouse model of frontotemporal dementia.
Terreros-Roncal J, Flor-García M, Moreno-Jiménez EP, Pallas-Bazarra N, Rábano A, Sah N, van Praag H, Giacomini D, Schinder AF, Ávila J, Llorens-Martín M, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 394 004 IHC; tested species: mouse

VIP-immunoreactive interneurons within circuits of the mouse basolateral amygdala.
Rhomberg T, Rovira-Esteban L, Vikór A, Paradiso E, Kremser C, Nagy-Pál P, Papp OI, Tasan R, Erdélyi F, Szabó G, Ferraguti F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 394 004 IHC; tested species: mouse

Cat. No.: 394 004

Amount: 100 µl

Price: $370.00

ICC

IHC

IHC-P

Background

Neuropeptide Y (NPY) is a 36-amino acid polypeptide that acts as a neurotransmitter in the brain and in the autonomic nervous system. It is produced and secreted by neurons of the sympathetic nervous system and neurons in the brain, e.g. the hypothalamus. NPY is involved in several physiological functions, including: increasing food intake and storage of energy as fat, reducing anxiety and stress, reducing pain perception, and lowering blood pressure.

1 ) Jacques D, Canadian journal of physiology and pharmacology (2017) 9510: 1224-1229.
2 ) Shi Z, The Journal of clinical investigation (2017) 1277: 2868-2880.
3 ) Rodnoi P, JCI insight (2017) 212: .
4 ) Kanevskij M, Cardiovascular research (2002) 534: 879-87.
5 ) Compan V, Brain research (1998) 7951-2: 264-76.

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Neuropeptide Y antibody - 394 004

References for Neuropeptide Y - 394 004