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TMEM119 antibody human specific - 400 111

TMEM119 is a microglia specific transmembrane protein
Mouse monoclonal purified IgG
Cat. No.: 400 111
Amount: 100 µg
Price: $415.00
Cat. No. 400 111 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: 1 : 1000 gallery  
Clone 61F9F2
Subtype IgG2b (κ light chain)
Immunogen Recombinant protein corresponding to AA 194 to 283 from human TMEM119 (UniProt Id: Q4V9L6)
Reactivity Reacts with: human (Q4V9L6).
Other species not tested yet.
Remarks

This antibody is recommended for material from human only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.
Data sheet 400_111.pdf

References for TMEM119 - 400 111

p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia.
Lin H, Dixon SG, Hu W, Hamlett ED, Jin J, Ergul A, Wang GY
Molecular neurobiology (2022) 599: 5284-5298. 400 111 IHC-P; tested species: human
Cat. No.: 400 111
Amount: 100 µg
Price: $415.00
p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia.
Lin H, Dixon SG, Hu W, Hamlett ED, Jin J, Ergul A, Wang GY
Molecular neurobiology (2022) 599: 5284-5298. 400 111 IHC-P; tested species: human
IHC-P
Background

Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.
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