| Cat. No. 400 121 |
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: 1 : 1000 gallery |
| Clone | 26C4B3 |
| Subtype | IgG2a (κ light chain) |
| Immunogen | Recombinant protein corresponding to AA 194 to 283 from human TMEM119 (UniProt Id: Q4V9L6) |
| Reactivity |
Reacts with: human (Q4V9L6). Other species not tested yet. |
| Remarks |
This antibody is recommended for material from human only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely. |
| Data sheet | 400_121.pdf |
Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.