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TMEM119 antibody - 400 203

TMEM119 is a microglia specific transmembrane protein
Rabbit polyclonal purified antibody
Cat. No.: 400 203
Amount: 50 µg
Price: $375.00
Cat. No. 400 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: not recommended
Immunogen Recombinant protein corresponding to AA 189 to 283 from rat TMEM119 (UniProt Id: B2RYL3)
Reactivity Reacts with: rat (B2RYL3).
Weaker signal: mouse (Q8R138).
Other species not tested yet.
Data sheet 400_203.pdf

References for TMEM119 - 400 203

Significant Sex Differences in the Efficacy of the CSF1R Inhibitor-PLX5622 on Rat Brain Microglia Elimination.
Sharon A, Erez H, Spira ME
Pharmaceuticals (Basel, Switzerland) (2022) 155: . 400 203 IHC; tested species: rat
Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications.
Sharon A, Jankowski MM, Shmoel N, Erez H, Spira ME
Frontiers in neuroscience (2021) 15: 646914. 400 203 IHC; tested species: rat
Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality.
Huang SH, Shmoel N, Jankowski MM, Erez H, Sharon A, Abu-Salah W, Nelken I, Weiss A, Spira ME
Frontiers in neuroscience (2020) 14: 926. 400 203 IHC; tested species: rat
Cat. No.: 400 203
Amount: 50 µg
Price: $375.00
Significant Sex Differences in the Efficacy of the CSF1R Inhibitor-PLX5622 on Rat Brain Microglia Elimination.
Sharon A, Erez H, Spira ME
Pharmaceuticals (Basel, Switzerland) (2022) 155: . 400 203 IHC; tested species: rat
Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications.
Sharon A, Jankowski MM, Shmoel N, Erez H, Spira ME
Frontiers in neuroscience (2021) 15: 646914. 400 203 IHC; tested species: rat
Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality.
Huang SH, Shmoel N, Jankowski MM, Erez H, Sharon A, Abu-Salah W, Nelken I, Weiss A, Spira ME
Frontiers in neuroscience (2020) 14: 926. 400 203 IHC; tested species: rat
IHC
Background

Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.
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