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TMEM119 antibody rat specific - 400 211

TMEM119 is a microglia specific transmembrane protein
Mouse monoclonal purified IgG
Cat. No.: 400 211
Amount: 100 µg
Price: $415.00
Cat. No. 400 211 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P: 1 : 1000 gallery  
Clone 97G1C1
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 189 to 283 from rat TMEM119 (UniProt Id: B2RYL3)
Reactivity Reacts with: rat (B2RYL3).
Other species not tested yet.
Remarks

This antibody is recommended for rat only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.
Data sheet 400_211.pdf

References for TMEM119 - 400 211

Neurosteroid [3α,5α]-3-Hydroxy-pregnan-20-one Enhances the CX3CL1-CX3CR1 Pathway in the Brain of Alcohol-Preferring Rats with Sex-Specificity.
Balan I, Grusca A, Chéry SL, Materia BR, O'Buckley TK, Morrow AL
Life (Basel, Switzerland) (2024) 147: . 400 211 IHC; tested species: rat
Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state.
Voshart DC, Oshima T, Jiang Y, van der Linden GP, Ainslie AP, Reali Nazario L, van Buuren-Broek F, Scholma AC, van Weering HRJ, Brouwer N, Sewdihal J, et al.
Cell reports (2024) 432: 113764. 400 211 IHC; tested species: rat
Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection.
Reid MM, Belayev L, Khoutorova L, Mukherjee PK, Obenaus A, Shelvin K, Knowles S, Hong SH, Bazan NG
Scientific reports (2023) 131: 15841. 400 211 IHC; tested species: rat
Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament.
Grotegut P, Kuehn S, Dick HB, Joachim SC
International journal of molecular sciences (2020) 212: . 400 211 IHC; tested species: rat
Cat. No.: 400 211
Amount: 100 µg
Price: $415.00
Neurosteroid [3α,5α]-3-Hydroxy-pregnan-20-one Enhances the CX3CL1-CX3CR1 Pathway in the Brain of Alcohol-Preferring Rats with Sex-Specificity.
Balan I, Grusca A, Chéry SL, Materia BR, O'Buckley TK, Morrow AL
Life (Basel, Switzerland) (2024) 147: . 400 211 IHC; tested species: rat
Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state.
Voshart DC, Oshima T, Jiang Y, van der Linden GP, Ainslie AP, Reali Nazario L, van Buuren-Broek F, Scholma AC, van Weering HRJ, Brouwer N, Sewdihal J, et al.
Cell reports (2024) 432: 113764. 400 211 IHC; tested species: rat
Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection.
Reid MM, Belayev L, Khoutorova L, Mukherjee PK, Obenaus A, Shelvin K, Knowles S, Hong SH, Bazan NG
Scientific reports (2023) 131: 15841. 400 211 IHC; tested species: rat
Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament.
Grotegut P, Kuehn S, Dick HB, Joachim SC
International journal of molecular sciences (2020) 212: . 400 211 IHC; tested species: rat
IHC
IHC
IHC-P
Background

Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.
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