GLUT1 antibody - 419 005

GLUT1 is a major glucose transporter in the mammalian blood-brain barrier
Guinea pig polyclonal purified antibody
Cat. No.: 419 005
Amount: 50 µg
Price: $460.00
Cat. No. 419 005 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery  
IHC-P: 1 : 100 gallery  
IHC-Fr: 1 : 500 (see remarks) gallery  
Immunogen Synthetic peptide corresponding to AA 229 to 240 from mouse GluT1 (UniProt Id: P17809)
Reactivity Reacts with: mouse (P17809), rat (P11167).
Other species not tested yet.
Remarks

IHC: Antigen retrieval (10mM citrate, pH 6.0, overnight at 60°C) is recommended.
IHC-Fr: MeOH fixation is recommended.

Data sheet 419_005.pdf
Cat. No.: 419 005
Amount: 50 µg
Price: $460.00
Background

Glucose transporter type 1 (GLUT1), also known as SLC2A1, is ubiquitously expressed, and is present at high levels in primate erythrocytes and brain endothelial cells. GLUT1 is a major glucose transporter in the mammalian blood-brain barrier and  is also able to transport dehydroascorbic acid (oxidized vitamin C) into the brain. GLUT1 may also contribute to HTLV-associated disorders through interactions with HTLV envelope glycoproteins.