Cat. No.: HS-351 004
Amount: 100 µl
Price:
$350.00
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| Cat. No. HS-351 004 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 26 to 601 from human CD31 (UniProt Id: P16284) |
| Reactivity |
Reacts with: human (P16284). No signal: mouse (Q08481). Other species not tested yet. |
| Data sheet | hs-351_004.pdf |
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Visualization of blood vessels in a human invasive ductal breast cancer section using anti-CD31 antibody.
CD31 or Platelet/endothelial cell adhesion molecule-1 (PECAM-1) is a cell adhesion molecule that contains a single trans-membrane domain and 6 Ig-like C2-type (immunoglobulin-like) domains (1). It is expressed on the surface of leukocytes and platelets and is primarily concentrated at endothelial cell-cell junctions (2). CD31 plays a role in several important biological processes, such as vascular development, maintenance of vascular endothelial barrier function and leukocyte emigration at inflammatory sites. In addition, CD31 promotes cancer metastasis by inducing epithelial epithelial-mesenchymal transition (3).