CD31 antibody mouse specific - HS-351 117

CD31 is an endothelial cell marker
Rat monoclonal purified IgG
Cat. No.: HS-351 117
Amount: 100 µg
Price: $415.00
Cat. No. HS-351 117 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 1000 gallery  
IHC-Fr: 1 : 500 (see remarks) gallery  
Clone SY-53A2
Subtype IgG2a (κ light chain)
Immunogen Synthetic peptide corresponding to residues surrounding AA 680 of mouse CD31 (UniProt Id: Q08481)
Reactivity Reacts with: mouse (Q08481), rat.
No signal: human (P16284).
Other species not tested yet.
Remarks

IHC-Fr: PFA fixation is recommended.

Data sheet hs-351_117.pdf
Cat. No.: HS-351 117
Amount: 100 µg
Price: $415.00

CD31 visualizes blood vessels in mouse small intestine

Background

CD31 or platelet/endothelial cell adhesion molecule-1 (PECAM-1) is a cell adhesion molecule that contains a single trans-membrane domain and 6 Ig-like C2-type (immunoglobulin-like) domains (1). It is expressed on the surface of leukocytes and platelets and is primarily concentrated at endothelial cell-cell junctions (2). CD31 plays a role in several important biological processes, such as vascular development, maintenance of vascular endothelial barrier function and leukocyte emigration at inflammatory sites. In addition, CD31 promotes cancer metastasis by inducing epithelial-mesenchymal transition (3).