|Cat. No. HS-361 003||200 µl specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C to -80°C until use.|
IHC: 1 : 100 (see remarks) gallery
IHC-P/FFPE: 1 : 100 gallery
|Immunogen||Synthetic peptide corresponding to AA 230 to 247 from mouse CD8a (UniProt Id: P01731)|
Reacts with: mouse (P01731).
Weaker signal: rat.
No signal: human.
Other species not tested yet.
|Specificity||Specific for CD8a.|
IHC: Heat-mediated antigen retrieval (in citrate buffer pH 6) is required for immunohistochemical stainings.
CD8 positive T-cells in FFPE mouse spleen section
CD 8 is a heterodimeric T-cell surface glycoprotein that consists of a CD 8a (alpha) and beta chain. It identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD 8 is thought to play a role in the process of T-cell mediated killing. CD 8 alpha chains binds to class I MHC molecules alpha-3 domains.