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LAMP3 antibody - HS-391 017 K.O.

LAMP3 is a glycoprotein of the lysosomal membrane
Rat monoclonal purified antibody
Cat. No.: HS-391 017
Amount: 100 µg
Price: $415.00
Cat. No. HS-391 017 100 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
IHC: not recommended
IHC-P: 1 : 200 up to 1 : 1000 gallery  
Clone SY-354H7
Subtype IgG2a (κ light chain)
Immunogen Synthetic peptide corresponding to C-terminal residues of mouse LAMP3. (UniProt Id: Q7TST5)
Reactivity Reacts with: mouse (Q7TST5), rat (Q5XI99), human (Q9UQV4).
Other species not tested yet.
Specificity Recognizes LAMP 3, no crossreactivity to LAMP 1, LAMP 2 and LAMP 5. K.O. validated
Data sheet hs-391_017.pdf
Cat. No.: HS-391 017
Amount: 100 µg
Price: $415.00

LAMP3 / DC-LAMP positive mature dendritic cells in human squamous cell carcinoma lymph node metastasis


LAMP 3 (lysosome-associated membrane glycoprotein 3), also referred to as DC-LAMP (dendritic cell LAMP) or CD 208, is a member of the LAMP protein family and a single-pass type I transmembrane protein that can be variably glycosylated. It is specifically expressed in lung type II pneumocytes and by activated human dendritic cells (1, 2).
Recent studies demonstrated high expression of LAMP 3 in a variety of malignancies including squamous cell carcinoma, gastrointestinal cancer, breast cancer, ovarian cancer, and cervical cancer. Its expression has been associated with metastasis and poor overall survival (3, 4, 5).

Protocols for HS-391 017