|Cat. No. HS-427 017||200 µl purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C to -80°C until use.|
IHC: 1 : 100 gallery
IHC-P/FFPE: 1 : 100 gallery
|Immunogen||Synthetic peptide corresponding to AA 1284 to 1291 from mouse PTPRC (UniProt Id: P06800-1)|
Epitop: AA 1284 to 1291 from mouse PTPRC (UniProt Id: P06800-1)
Reacts with: mouse (P06800-1).
No signal: human.
Other species not tested yet.
|Specificity||The antibody recognizes all CD45 isoforms.|
CD45 positive cells in FFPE mouse tissues
CD 45, also designated as Leucocyte Common Antigen (LCA) or Protein tyrosine phosphatase receptor type C (PTPRC), is a type I transmembrane protein expressed on all leukocytes. CD 45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. Several isoforms of CD 45 have been identified, the expression of which differs according to cell type and functional status. Clone GHH45 is raised against a conserved region at the C-terminus of CD 45.