CD11c antibody - HS-375 004

CD11c is a fibrinogen receptor involved in cell-cell interaction during inflammation
Guinea pig polyclonal antiserum
Cat. No.: HS-375 004
Amount: 100 µl
Price: $350.00
Cat. No. HS-375 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
IHC: 1 : 1000 gallery  
IHC-P: 1 : 500 up to 1 : 2000 gallery  
Immunogen Synthetic peptide corresponding to AA 1159 to 1169 from mouse CD11c (UniProt Id: Q9QXH4)
Reactivity Reacts with: mouse (Q9QXH4).
No signal: human (P20702), rat.
Other species not tested yet.
Matching control protein/peptide 375-0P
Data sheet hs-375_004.pdf
Cat. No.: HS-375 004
Amount: 100 µl
Price: $350.00

CD11c positive cells in FFPE mouse spleen section

CD 11c or Integrin alpha-X (ITGAX) is a heterodimeric glycoprotein consisting of an α- and β-subunit and has seven repeating integrin domains. This transmembrane receptor type I plays a pivotal role in T cell killing and mediates intercellular adhesions during inflammation. Predominat expression levels have been found in dendritic cells, monocytes, macrophages, neutrophils and a small subset of B cells. Under pathological conditions, CD 11c is a marker for hairy cell leukemia, acute non-lymphocytic leukemias, and some chronic lymphocytic leukemias.
Protocols for HS-375 004