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CD 11c - HS-375 004

A fibrinogen receptor involved in cell-cell interaction during inflammation
Polyclonal Guinea pig antiserum
Cat. No.: HS-375 004
Amount: 100 µl
Price: 350.00 €
Cat. No. HS-375 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications IHC: 1 : 1000 gallery  
IHC-P/FFPE: 1 : 500 up to 1 : 2000 gallery  
Immunogen Synthetic peptide corresponding to AA 1159 to 1169 from mouse CD11c (UniProt Id: Q9QXH4)
Reactivity Reacts with: mouse (Q9QXH4).
Other species not tested yet.
Specificity Specific for CD 11c.
Data sheet hs-375_004.pdf
Cat. No.: HS-375 004
Quantity: 100 µl
Price: 350.00 €

CD11c positive cells in FFPE mouse spleen section

Background
CD 11c or Integrin alpha-X (ITGAX) is a heterodimeric glycoprotein consisting of an α- and β-subunit and has seven repeating integrin domains. This transmembrane receptor type I plays a pivotal role in T cell killing and mediates intercellular adhesions during inflammation. Predominat expression levels have been found in dendritic cells, monocytes, macrophages, neutrophils and a small subset of B cells. Under pathological conditions, CD 11c is a marker for hairy cell leukemia, acute non-lymphocytic leukemias, and some chronic lymphocytic leukemias.
Protocols